GHOST-MP is a parallel sequence similarity search tool. It searches for similar sequences among nucleotide query sequences and amino acid sequence database like BLASTX. GHOST-MP runs on a distributed memory system and processes query sequences in parallel. It could run on over 100,000 CPU cores.

GHOST-MP’s sequence similarity search is based on GHOSTX’s search algorithm. GHOSTX is sequence similarity search tool with suffix arrays and is more than 100 times faster than BLASTX. GHOST-MP parallelize GHOSTX’s search algorithm using Message Passing Interface library and could be run on massively parallel distributed memory systems such as K computer at RIKEN Advanced Institute for Computational Science and TSUBAME 2.5 at Tokyo Institute of Technology.