研究メモ/protein affinity benchmarks

研究メモ

Protein–protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area - Chen - 2013 - Protein Science - Wiley Online Library http://onlinelibrary.wiley.com/doi/10.1002/pro.2230/full

Protein Affinity Benchmark †

• http://bmm.cancerresearchuk.org/~bmmadmin/Affinity/
  • 1NVU (1NVU complex with chain Q:S) and 5NVU (1NVU complex with chain R:S)

References

• Kastritis, P. L., Moal, I. H., Hwang, H., Weng, Z., Bates, P. a, Bonvin, A. M. J. J., & Janin, J. (2011). A structure-based benchmark for protein-protein binding affinity. Protein science : a publication of the Protein Society, 20(3), 482-91. doi:10.1002/pro.580
• Kastritis, P. L., & Bonvin, A. M. J. J. (2010). Are Scoring Functions in Protein-Protein Docking Ready To Predict Interactomes? Clues from a Novel Binding Affinity Benchmark. Journal of proteome research, 9(5), 2216–2225. ACS Publications. doi:10.1021/pr9009854